CC-6043 PH198 x CC-124 [PH210]

$30.00

Deposited by Olga Baidukova, Peter Hegemann lab, Humboldt University-Berlin, July 2023

This is a strain with a point mutation E90Q in ChR2 and disrupted ChR1, which was generated with CRISPR/Cas9. The original strain PH198 with CC125 as a background was crossed into CC124.

Background strain: PH198, CC124 mt-
Nuclease: (Sp)Cas9 as ribonucleoprotein (RNP)
Target gene: ChR1, Cre14.g611300; ChR2, Cre02.g085257
Target sequence: TGTGGCTTCGTTACGCGGAG (ChR1); CTATGTGTGCGCTATCGAGG (ChR2)

Overview of all CRISPR/Cas9 strains from the Hegemann lab

http://www.chlamy.de/strains

Visit www.chlamy.de for more info or contact CRISPR@chlamy.de

This is an unpublished strain. Please contact ph@chlamy.de before using it.