The use of whole genome sequencing to identify mutant lesions

Lin H, Miller ML, Granas DM, Dutcher SK. Whole genome sequencing identifies a deletion in protein phosphatase 2A that affects its stability and localization inChlamydomonas reinhardtii. PLoS Genet. 2013;9(9):e1003841. doi: 10.1371/journal.pgen.1003841. Epub 2013 Sep 26. PubMed PMID: 24086163; PubMed Central PMCID: PMC3784568.

Research positions in microalgal cell biology

Temporary Full Time Technician, Scientist and Intern Research positions in microalgal cell biology: Full time (1-2 years) for a research technician, scientist and intern in a research project focusing on protein expression in microalgae algae at North Carolina Central University located at the North Carolina Research Campus in Kannapolis (20 minutes from Charlotte). Job Description: Primary … Continued

Chlamy mutant library, update

Dear Chlamy community, We have set up another opportunity for labs who haven’t yet received a mutant from the pilot collection to obtain one [see previous announcement below, posted in December]. If you are interested, please see the website below and use the form at the bottom to submit a request by June 23rd, 2014. … Continued

Batch conversion of Chlamydomonas gene identifiers

The tool for converting batches of Chlamydomonas gene identifiers between different annotation versions has been updated to include all versions from JGI v3 onwards. The tool is available here: http://pathways.mcdb.ucla.edu/algal/id_conversion.html The versions that can be converted are JGI v3, v4, v4.3 (Augustus u10.2), v5.3.1, v5.5 as well as Augustus u5 and u9 and GenBank accessions … Continued

Chlamy mutant library

Dear Chlamy community, Thanks to letters of support from many of you, the Chlamy mutant library project is now well underway, and we currently have a pilot collection covering ~10% of all genes. While the paper is still a ways away, we have received many requests for collaborative distribution of individual mutants before we publish. … Continued

BAC library is OK

From Olivier Vallon, IBPC, Paris: Recently, concerns were raised about possible plate swaps in the BAC library distributed by Clemson University Genomics Institute and sequenced by JGI under the accessions PTQ…. While the copy #23 received by the Paris group indeed suffers from plate swaps, this seems to be due to a one-time error of … Continued

BAC library debugged

From Katia Wostrikoff and Olivier Vallon, IBPC, Paris: While trying to complement mutations in specific regions of the genome using the BAC library from the Silflow/Lefebvre labs, we have come to realize that for many plates, the sequences indicated by the JGI browser (http://genome.jgi-psf.org/Chlre4/Chlre4.home.html) were not correct. We have systematically sequenced BAC ends from all … Continued