P-228 cpDNA BamHI-HindIII (4.8 kb) spr-u-1-6-2
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Boynton-Gillham laboratory, Duke University, 1989
Chloroplast DNA Bam-HindIII (4.8 kb) in pUC18; 16S through 5′ part of 23S rRNA gene; from CC-110, contains spectinomycin resistance mutation spr-u-1-6-2; see P-667 for the same insert in an XL1 blue strain
host strain: JM83
amp resistant
More information
Strain: CC-110 spr-u-1-6-2 mt+
Insert: BamHI-HindIII (4.8 kb) from BamHI 11/12
Genes present: 16S rRNA, 23Ss rRNA (5′ end)
Vector: pUC18
Bacterial host strain: JM83
Selectable marker: amp-r, white on X-gal
Origin: Scott Newman in Boynton/Gillham lab, 1989
The spr-u-1-6-2 mutations is an A-> G change at bp 1123 in the C. reinhardtii 16S rRNA gene which causes loss of an AatII restriction site and confers high level spectinomycin resistance. See Harris et al., Genetics 123, 281-292 (1989). Used in rRNA transformation experiments by Newman et al., Genetics 126, 875-888 (1990).