From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: requires acetate, sensitive to light, lacks the cell wall

This strain was recovered by Bryan D. Smith in Spreitzer’s group from a cross between prk1-Δ50 mt+ and cwd arg7-8 mt- (CC-3395). The cwd arg7-8 mt- strain (Gumpel et al. 1994) was obtained from Don Weeks in 1994. This prk1-Δ50 cwd arg7-8 mt- strain lacks phosphoribulokinase activity and protein due to a 50-bp deletion in prk1 (Smith 2000), and may serve as a host for transformation with engineered prk1 genes. This strain has been maintained with acetate medium in darkness since its isolation. For unknown reasons, it no longer requires Arg for growth.


Gumpel NJ, Rochaix JD, Purton S (1994) Studies on homologous recombination in the green alga Chlamydomonas reinhardtii. Curr Genet 26:438-442

Smith BD (2000) Isolation and analysis of Chlamydomonas reinhardtii phosphoribulokinase mutants and revertants. Undergraduate Honors Thesis, Department of Biochemistry, University of Nebraska (available from the Chlamydomonas Resource Center)


  • Locus:
  • AC214 [PRK1]
  • Chromosome:
  • 12

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: requires acetate, sensitive to light, lacks the cell wall

Bryan D. Smith in Spreitzer’s group transformed prk1-Δ50 cwd arg7-8 mt- with pARG7.8 (Gumpel et al. 1994) to eliminate the Arg requirement. This prk1-Δ50 cwd mt- strain lacks phosphoribulokinase activity and protein due to a 50-bp deletion in prk1 (Smith 2000), and may serve as a host for transformation with engineered prk1 genes. It has been maintained with acetate medium in darkness since its isolation.


Gumpel NJ, Rochaix JD, Purton S (1994) Studies on homologous recombination in the green alga Chlamydomonas reinhardtii. Curr Genet 26:438-442

Smith BD (2000) Isolation and analysis of Chlamydomonas reinhardtii phosphoribulokinase mutants and revertants. Undergraduate Honors Thesis, Department of Biochemistry, University of Nebraska (available from the Chlamydomonas Resource Center)


  • Locus:
  • AC214 [PRK1]
  • Chromosome:
  • 12

From Robert J. Spreitzer, University of Nebraska, March 2014

Following MMS mutagenesis of prk1-E267Amber mt- (GAG-TAG), Bryan Smith in Spreitzer’s group selected photosynthesis-competent revertants at a frequency of 1 X 10E-7 cells (Smith 2000). Revertant R190-1C has reduced photosynthetic growth relative to wild type, but has a normal level of phosphoribulokinase protein. It was found to result from a pseudoreversion substitution that converts the amber mutation (TAG) to Lys (AAG). The mutant protein has not been analyzed. This strain has been maintained with acetate medium in darkness since its isolation.


Smith BD (2000) Isolation and analysis of Chlamydomonas reinhardtii phosphoribulokinase mutants and revertants. Undergraduate Honors Thesis, Department of Biochemistry, University of Nebraska (available from the Chlamydomonas Resource Center)


  • Locus:
  • AC214 [PRK1]
  • Chromosome:
  • 12

From Robert J. Spreitzer, University of Nebraska, March 2014

Following MMS mutagenesis of prk1-E267Amber mt- (GAG-TAG), Bryan Smith in Spreitzer’s group selected photosynthesis-competent revertants at a frequency of 1 X 10E-7 cells (Smith 2000). Revertant R190-3A has normal photosynthetic growth relative to wild type, and has a normal level of phosphoribulokinase protein. It was found to result from a pseudoreversion substitution that converts the amber mutation (TAG) to Gln (CAG). The mutant protein has not been analyzed. This strain has been maintained with acetate medium in darkness since its isolation.


Smith BD (2000) Isolation and analysis of Chlamydomonas reinhardtii phosphoribulokinase mutants and revertants. Undergraduate Honors Thesis, Department of Biochemistry, University of Nebraska (available from the Chlamydomonas Resource Center)


  • Locus:
  • AC214 [PRK1]
  • Chromosome:
  • 12

From Robert J. Spreitzer, University of Nebraska, March 2014

Following MMS mutagenesis of prk1-R64C mt+ (CGC-TGC), Bryan Smith in Spreitzer’s group selected photosynthesis-competent revertants at a frequency of 1 X 10E-8 cells (Smith 2000). Revertant R175-3A has reduced photosynthetic growth relative to wild type. It was found to result from intragenic suppression that converts phosphoribulokinase Ile-28 (ATC) to Met (ATG). The mutant protein has not been analyzed. This strain has been maintained with acetate medium in darkness since its isolation.


Smith BD (2000) Isolation and analysis of Chlamydomonas reinhardtii phosphoribulokinase mutants and revertants. Undergraduate Honors Thesis, Department of Biochemistry, University of Nebraska (available from the Chlamydomonas Resource Center)


  • Locus:
  • AC214 [PRK1]
  • Chromosome:
  • 12

From Robert J. Spreitzer, University of Nebraska, March 2014

Following MMS mutagenesis of prk1-R64C mt+ (CGC-TGC), Bryan Smith in Spreitzer’s group selected photosynthesis-competent revertants at a frequency of 1 X 10E-8 cells (Smith 2000). Revertant R191-1B has reduced photosynthetic growth relative to wild type. It was found to result from intragenic suppression that converts phosphoribulokinase Ile-28 (ATC) to Ser (AGC). The mutant protein has not been analyzed. This strain has been maintained with acetate medium in darkness since its isolation.


Smith BD (2000) Isolation and analysis of Chlamydomonas reinhardtii phosphoribulokinase mutants and revertants. Undergraduate Honors Thesis, Department of Biochemistry, University of Nebraska (available from the Chlamydomonas Resource Center)


  • Locus:
  • AC214 [PRK1]
  • Chromosome:
  • 12

From Robert J. Spreitzer, University of Nebraska, March 2014

Following MMS mutagenesis of prk1-R64C mt+ (CGC-TGC), Bryan Smith in Spreitzer’s group selected photosynthesis-competent revertants at a frequency of 1 X 10E-8 cells (Smith 2000). Revertant R203-16A has reduced photosynthetic growth relative to wild type. It was found to result from intragenic suppression that converts phosphoribulokinase Gly-326 (GGC) to Ser (AGC). The mutant protein has not been analyzed. This strain has been maintained with acetate medium in darkness since its isolation.


Smith BD (2000) Isolation and analysis of Chlamydomonas reinhardtii phosphoribulokinase mutants and revertants. Undergraduate Honors Thesis, Department of Biochemistry, University of Nebraska (available from the Chlamydomonas Resource Center)


  • Locus:
  • AC214 [PRK1]
  • Chromosome:
  • 12

From Robert J. Spreitzer, University of Nebraska, March 2014

Following MMS mutagenesis of prk1-R64C mt+ (CGC-TGC), Bryan Smith in Spreitzer’s group selected photosynthesis-competent revertants at a frequency of 1 X 10E-8 cells (Smith 2000). Revertant R212-14A has reduced photosynthetic growth relative to wild type. It was found to result from intragenic suppression that converts phosphoribulokinase Ser-148 (TCC) to Phe (TTC). The mutant protein has not been analyzed. This strain has been maintained with acetate medium in darkness since its isolation.


Smith BD (2000) Isolation and analysis of Chlamydomonas reinhardtii phosphoribulokinase mutants and revertants. Undergraduate Honors Thesis, Department of Biochemistry, University of Nebraska (available from the Chlamydomonas Resource Center)


  • Locus:
  • AC214 [PRK1]
  • Chromosome:
  • 12

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: requires elevated CO2 for photosynthetic growth, zeocin resistant

This Rubisco activase knock-out mutant was received from Jim Moroney in 2006 (Pollock et al. 2003). It has been maintained with acetate medium in darkness to prevent selection for extragenic suppressors. The CO2-requiring phenotype may be easier to observe with 10-25 µM ethoxzolamide in the minimal medium plates.


Pollock SV, Colombo SL, Prout DL, Godfrey AC, Moroney JV (2003) Rubisco activase is required for optimal photosynthesis in the green alga Chlamydomonas reinhardtii in a low-CO2 atmosphere. Plant Physiol 133:1854-1861


  • Locus:
  • RCA1
  • Chromosome:
  • 4

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: requires elevated CO2 for photosynthetic growth

This strain was received from Kensaku Suzuki in 2011. It was originally recovered as an acetate-requiring mutant (Spreitzer and Ogren 1983). Subsequent screening found it to be rescued by elevated CO2, and deficient in phosphoglycolate phosphatase activity (Suzuki et al. 1990). The strain has been maintained with acetate medium in darkness since 2011.


Spreitzer RJ, Ogren WL (1983) Rapid recovery of chloroplast mutations affecting ribulosebisphosphate carboxylase/oxygenase in Chlamydomonas reinhardtii. Proc Natl Acad Sci USA 80:6293-6297

Suzuki K, Marek LF, Spalding MH (1990) A photorespiratory mutant of Chlamydomonas reinhardtii. Plant Physiol 93:231-237

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: requires elevated CO2 for photosynthetic growth

This strain was received from Kensaku Suzuki in 2011 as a progeny clone of 18-7F obtained after five crosses with CC-125. 18-7F was originally recovered as an acetate-requiring mutant (Spreitzer and Ogren 1983). Subsequent screening found it to be rescued by elevated CO2, and deficient in phosphoglycolate phosphatase activity (Suzuki et al. 1990). The strain has been maintained with acetate medium in darkness since 2011.


Spreitzer RJ, Ogren WL (1983) Rapid recovery of chloroplast mutations affecting ribulosebisphosphate carboxylase/oxygenase in Chlamydomonas reinhardtii. Proc Natl Acad Sci USA 80:6293-6297

Suzuki K, Marek LF, Spalding MH (1990) A photorespiratory mutant of Chlamydomonas reinhardtii. Plant Physiol 93:231-237

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: altered CO2 assimilation

This mutant has the Rubisco small subunit replaced with an engineered spinach small subunit that has alpha-helix A replaced with the Chlamydomonas alpha-helix A (Meyer et al. 2012). It lacks the pyrenoid and the CO2 concentrating mechanism (CCM), and requires elevated CO2 for a wild-type level of photosynthetic growth. The strain has been maintained with acetate medium in darkness since its creation.


Meyer MT, Genkov T, Skepper JN, Jouhet J, Mitchell MC, Spreitzer RJ, Griffiths H (2012) Rubisco small-subunit α-helices control pyrenoid formation in Chlamydomonas. Proc Natl Acad Sci USA 109:19474-19479


  • Locus:
  • RBCS1
  • Chromosome:
  • 2

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: altered CO2 assimilation

This mutant has the Rubisco small subunit replaced with an engineered spinach small subunit that has alpha-helix B replaced with the Chlamydomonas alpha-helix B (Meyer et al. 2012). It lacks the pyrenoid and the CO2 concentrating mechanism (CCM), and requires elevated CO2 for a wild-type level of photosynthetic growth. The strain has been maintained with acetate medium in darkness since its creation.


Meyer MT, Genkov T, Skepper JN, Jouhet J, Mitchell MC, Spreitzer RJ, Griffiths H (2012) Rubisco small-subunit α-helices control pyrenoid formation in Chlamydomonas. Proc Natl Acad Sci USA 109:19474-19479


  • Locus:
  • RBCS1
  • Chromosome:
  • 2

From Robert J. Spreitzer, University of Nebraska, March 2014

This mutant has the Rubisco small subunit replaced with an engineered spinach small subunit that has alpha-helixes A and B replaced with the Chlamydomonas alpha-helixes A and B (Meyer et al. 2012). It has a pyrenoid and the CO2 concentrating mechanism (CCM), and near-normal CO2 assimilation for photosynthetic growth. The strain has been maintained with acetate medium in darkness since its creation.


Meyer MT, Genkov T, Skepper JN, Jouhet J, Mitchell MC, Spreitzer RJ, Griffiths H (2012) Rubisco small-subunit α-helices control pyrenoid formation in Chlamydomonas. Proc Natl Acad Sci USA 109:19474-19479


  • Locus:
  • RBCS1
  • Chromosome:
  • 2

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: requires elevated CO2 for photosynthetic growth

This strain was originally recovered as an acetate-requiring mutant (Spreitzer and Mets 1981). Subsequent screening found it to be rescued by elevated CO2, and deficient in carbonic anhydrase activity (Spalding et al. 1983). The strain has been maintained with acetate medium in darkness since its isolation.


Spreitzer RJ, Mets L (1981) Photosynthesis-deficient mutants of Chlamydomonas reinhardtii with associated light-sensitive phenotypes. Plant Physiol 67:565-569

Spalding MH, Spreitzer RJ, Ogren WL (1983) Carbonic anhydrase-deficient mutant of Chlamydomonas reinhardii requires elevated carbon dioxide concentration for photoautotrophic growth. Plant Physiol 73:268-272


  • Locus:
  • CAH3
  • Chromosome:
  • 9

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: requires elevated CO2 for photosynthetic growth

Mutant 12-1C mt+ was crossed with pf2 mt-, and this mt- progeny clone was retained for further genetic analysis. Mutant 12-1C was originally recovered as an acetate-requiring mutant (Spreitzer and Mets 1981). Subsequent screening found it to be rescued by elevated CO2, and deficient in carbonic anhydrase activity (Spalding et al. 1983). This strain has been maintained with acetate medium in darkness since its isolation.


Spreitzer RJ, Mets L (1981) Photosynthesis-deficient mutants of Chlamydomonas reinhardtii with associated light-sensitive phenotypes. Plant Physiol 67:565-569

Spalding MH, Spreitzer RJ, Ogren WL (1983) Carbonic anhydrase-deficient mutant of Chlamydomonas reinhardii requires elevated carbon dioxide concentration for photoautotrophic growth. Plant Physiol 73:268-272


  • Locus:
  • CAH3, PF2
  • Chromosome:
  • 9,11

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: requires elevated CO2 for photosynthetic growth

Mutant 12-1C mt+ was crossed with pf2 mt-, and this pf2 mt+ progeny clone was retained for further genetic analysis. Mutant 12-1C was originally recovered as an acetate-requiring mutant (Spreitzer and Mets 1981). Subsequent screening found it to be rescued by elevated CO2, and deficient in carbonic anhydrase activity (Spalding et al. 1983). This strain has been maintained with acetate medium in darkness since its isolation.


Spreitzer RJ, Mets L (1981) Photosynthesis-deficient mutants of Chlamydomonas reinhardtii with associated light-sensitive phenotypes. Plant Physiol 67:565-569

Spalding MH, Spreitzer RJ, Ogren WL (1983) Carbonic anhydrase-deficient mutant of Chlamydomonas reinhardii requires elevated carbon dioxide concentration for photoautotrophic growth. Plant Physiol 73:268-272


  • Locus:
  • CAH3, PF2
  • Chromosome:
  • 9,11

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: requires elevated CO2 for photosynthetic growth

Mutant 16-5K mt+ (CC-1860) was crossed with pf2 mt-, and this progeny clone was retained for further genetic analysis. Mutant 16-5K was originally recovered as an acetate-requiring mutant (Spreitzer and Ogren 1983). Subsequent screening found it to be rescued by elevated CO2, and deficient in inorganic carbon transport (Spalding et al. 1983). This strain has been maintained with acetate medium in darkness since its isolation.


Spreitzer RJ, Ogren WL (1983) Rapid recovery of chloroplast mutations affecting ribulosebisphosphate carboxylase/oxygenase in Chlamydomonas reinhardtii. Proc Natl Acad Sci USA 80:6293-6297

Spalding MH, Spreitzer RJ, Ogren WL (1983) Reduced inorganic carbon transport in a CO2-requiring mutant of Chlamydomonas reinhardii. Plant Physiol 73:273-276


  • Locus:
  • LCIB, PF2
  • Chromosome:
  • 10,11

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: requires elevated CO2 for photosynthetic growth

Mutant 16-5K mt+ (CC-1860) was crossed with pf2 mt-, and this progeny clone was retained for further genetic analysis. Mutant 16-5K was originally recovered as an acetate-requiring mutant (Spreitzer and Ogren 1983). Subsequent screening found it to be rescued by elevated CO2, and deficient in inorganic carbon transport (Spalding et al. 1983). This strain has been maintained with acetate medium in darkness since its isolation.


Spreitzer RJ, Ogren WL (1983) Rapid recovery of chloroplast mutations affecting ribulosebisphosphate carboxylase/oxygenase in Chlamydomonas reinhardtii. Proc Natl Acad Sci USA 80:6293-6297

Spalding MH, Spreitzer RJ, Ogren WL (1983) Reduced inorganic carbon transport in a CO2-requiring mutant of Chlamydomonas reinhardii. Plant Physiol 73:273-276


  • Locus:
  • LCIB, PF2
  • Chromosome:
  • 10,11

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: requires elevated CO2 for photosynthetic growth

Mutant 16-5K mt+ (CC-1860) was crossed with pf2 mt-, and this pf2 progeny clone was retained for further genetic analysis. Mutant 16-5K was originally recovered as an acetate-requiring mutant (Spreitzer and Ogren 1983). Subsequent screening found it to be rescued by elevated CO2, and deficient in inorganic carbon transport (Spalding et al. 1983). This strain has been maintained with acetate medium in darkness since its isolation.


Spreitzer RJ, Ogren WL (1983) Rapid recovery of chloroplast mutations affecting ribulosebisphosphate carboxylase/oxygenase in Chlamydomonas reinhardtii. Proc Natl Acad Sci USA 80:6293-6297

Spalding MH, Spreitzer RJ, Ogren WL (1983) Reduced inorganic carbon transport in a CO2-requiring mutant of Chlamydomonas reinhardii. Plant Physiol 73:273-276


  • Locus:
  • LCIB, PF2
  • Chromosome:
  • 10,11

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: requires elevated CO2 for photosynthetic growth

This double-mutant progeny clone was recovered from crosses between 12-1C and 16-5K (Spalding et al. 1983). The strain has been maintained with acetate medium in darkness since its isolation.


Spalding MH, Spreitzer RJ, Ogren WL (1983) Genetic and physiological analysis of the CO2-concentrating system of Chlamydomonas reinhardtii. Planta 159:261-266

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: requires elevated CO2 for photosynthetic growth

This double-mutant progeny clone was recovered from crosses between 12-1C and 16-5K (Spalding et al. 1983). The strain has been maintained with acetate medium in darkness since its isolation.


Spalding MH, Spreitzer RJ, Ogren WL (1983) Genetic and physiological analysis of the CO2-concentrating system of Chlamydomonas reinhardtii. Planta 159:261-266

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: requires elevated CO2 for photosynthetic growth

This double-mutant progeny clone was recovered from crosses between 12-1C and 16-5K (Spalding et al. 1983). The strain has been maintained with acetate medium in darkness since its isolation.


Spalding MH, Spreitzer RJ, Ogren WL (1983) Genetic and physiological analysis of the CO2-concentrating system of Chlamydomonas reinhardtii. Planta 159:261-266


  • Locus:
  • PF2
  • Chromosome:
  • 11

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: requires elevated CO2 for photosynthetic growth at 35 °C

A collection of over 350 acetate-requiring mutants (Spreitzer et al. 1988) was screened for those that could be rescued with 5% CO2 in air. This is one of seven genetically-independent mutants that was recovered. It grows on minimal medium at 25 °C, but dies on minimal medium at 35 °C. It can be rescued on minimal medium at 35 °C with 5% CO2 in air. It may be defective in the CO2-concentrating mechanism (CCM), but has not been analyzed. This nuclear mutant has been maintained with acetate medium in darkness since its isolation.


Spreitzer RJ, Al-Abed SR, Huether MJ (1988) Temperature-sensitive, photosynthesis-deficient mutants of Chlamydomonas reinhardtii. Plant Physiol 86:773-777

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: requires elevated CO2 for photosynthetic growth at 35 °C

This is an mt- progeny clone of a cross between 65-6A mt+ and “wild-type” mt-. It grows on minimal medium at 25 °C, but dies on minimal medium at 35 °C. It can be rescued on minimal medium at 35 °C with 5% CO2 in air. It may be defective in the CO2-concentrating mechanism (CCM), but has not been analyzed. This nuclear mutant has been maintained with acetate medium in darkness since its isolation.


Spreitzer RJ, Al-Abed SR, Huether MJ (1988) Temperature-sensitive, photosynthesis-deficient mutants of Chlamydomonas reinhardtii. Plant Physiol 86:773-777

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: requires elevated CO2 for photosynthetic growth at 35 °C

A collection of over 350 acetate-requiring mutants (Spreitzer et al. 1988) was screened for those that could be rescued with 5% CO2 in air. This is one of seven genetically-independent mutants that was recovered. It grows on minimal medium at 25 °C, but dies on minimal medium at 35 °C. It can be rescued on minimal medium at 35 °C with 5% CO2 in air. It may be defective in the CO2-concentrating mechanism (CCM), but has not been analyzed. This nuclear mutant has been maintained with acetate medium in darkness since its isolation.


Spreitzer RJ, Al-Abed SR, Huether MJ (1988) Temperature-sensitive, photosynthesis-deficient mutants of Chlamydomonas reinhardtii. Plant Physiol 86:773-777

From Robert J. Spreitzer, University of Nebraska, March 2014

Phenotype: requires elevated CO2 for photosynthetic growth at 35 °C

A collection of over 350 acetate-requiring mutants (Spreitzer et al. 1988) was screened for those that could be rescued with 5% CO2 in air. This is one of seven genetically-independent mutants that was recovered. It grows on minimal medium at 25 °C, but dies on minimal medium at 35 °C. It can be rescued on minimal medium at 35 °C with 5% CO2 in air. It may be defective in the CO2-concentrating mechanism (CCM), but has not been analyzed. This strain has been maintained with acetate medium in darkness since its isolation.


Spreitzer RJ, Al-Abed SR, Huether MJ (1988) Temperature-sensitive, photosynthesis-deficient mutants of Chlamydomonas reinhardtii. Plant Physiol 86:773-777

From Robert J. Spreitzer, University of Nebraska, March 2014

A collection of over 350 acetate-requiring mutants (Spreitzer et al. 1988) was screened for those that could be rescued with 5% CO2 in air. This is one of seven genetically-independent mutants that was recovered. It grows on minimal medium at 25 °C, but dies on minimal medium at 35 °C. It can be rescued on minimal medium at 35 °C with 5% CO2 in air. It may be defective in the CO2-concentrating mechanism (CCM), but has not been analyzed. This strain has been maintained with acetate medium in darkness since its isolation.


Spreitzer RJ, Al-Abed SR, Huether MJ (1988) Temperature-sensitive, photosynthesis-deficient mutants of Chlamydomonas reinhardtii. Plant Physiol 86:773-777

From Robert J. Spreitzer, University of Nebraska, March 2014

A collection of over 350 acetate-requiring mutants (Spreitzer et al. 1988) was screened for those that could be rescued with 5% CO2 in air. This is one of seven genetically-independent mutants that was recovered. It grows on minimal medium at 25 °C, but dies on minimal medium at 35 °C. It can be rescued on minimal medium at 35 °C with 5% CO2 in air. It may be defective in the CO2-concentrating mechanism (CCM), but has not been analyzed. This strain has been maintained with acetate medium in darkness since its isolation.


Spreitzer RJ, Al-Abed SR, Huether MJ (1988) Temperature-sensitive, photosynthesis-deficient mutants of Chlamydomonas reinhardtii. Plant Physiol 86:773-777

From Robert J. Spreitzer, University of Nebraska, March 2014

A collection of over 350 acetate-requiring mutants (Spreitzer et al. 1988) was screened for those that could be rescued with 5% CO2 in air. This is one of seven genetically-independent mutants that was recovered. It grows on minimal medium at 25 °C, but dies on minimal medium at 35 °C. It can be rescued on minimal medium at 35 °C with 5% CO2 in air. It may be defective in the CO2-concentrating mechanism (CCM), but has not been analyzed. This strain has been maintained with acetate medium in darkness since its isolation.


Spreitzer RJ, Al-Abed SR, Huether MJ (1988) Temperature-sensitive, photosynthesis-deficient mutants of Chlamydomonas reinhardtii. Plant Physiol 86:773-777